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Posts Tagged ‘University of Louisville’

The Ferocious Insectivore!

In Science, Science and Medical Research on November 2, 2011 at 6:22 pm

93-million-year-old mammal

An insectivore from South America

The charming little guys in the illustration above are the new best clue to what went on in mammalian evolution in the southern continents from 130 million years ago to 60 million years ago. Note what big teeth this insect-eater had. Nobody is sure just what they used those oversized canines for, unless Cretaceous-era insects put up a hell of a fight.

Probably no more than 4- to 6-inches long,  Cronopio dentiacutus  was about the right size to hide from the dinosaurs, the dominant life in the neighborhood. A paper about the discovery of inch-long Cronopio skulls is published in the November 3 edition of Nature. University of Louisville researcher Guillermo W. Rougier, an expert in mammalian evolution, is the lead author.

Rich Cifelli of the University of Oklahoma, who studies early mammals, called the skulls a “Rosetta Stone,” for mammalian evolution in the southern continents.

Ninety-three million years ago, South America was just breaking up from the supercontinent Gondwana, the land mass that included Africa, India, Australia and Antarctica. During Cronopio’s lifetime, Earth was a toasty place, with no polar ice caps. Although the continents were south of where they sit today, and Africa and South America were separated by an ocean no bigger than the Mediterranean Sea, the land was tropical.

The paper’s second author, Sebastian Apesteguia, discovered the Cronopio skulls embedded in rock in 2006. While the Argentine scientists worked to remove the skulls from the surrounding material, Rougier waited to see what emerged. An expert in mammalian evolution, Rougier has conducted field work  in China, Mongolia, Japan, and elsewhere.  When he saw photos of what was emerging in the Argentine laboratory, he was stunned.

“I could not believe those canines! I mean these are really large canines. I asked, ‘Are you sure they’re not falling out?’… I was dying to go down there and I flew away as soon as I could.”

The animals had long, tubular, pointy snouts and the triangular teeth of an insectivore — nothing too surprising there. But the big canines, about one-fifth the length of the head, have no precedent in a skull with this shape, Rougier says. “It’s a model for which we have no living representatives.”

Rougier, who will be 47 on November 4,  came to U of L in 1998 from the American Museum of Natural History in New York City. He grew up in Buenos Aires and dreamed of being a paleontologist since he was 7. Although his primary focus is on mammals, he has researched the origin of turtles, work featured on the cover of Science in 1996. His work on the origin of marsupials was on the cover of Nature in 1998.

Rougier said the skulls are only a single data point in the long history of mammalian evolution.

“We broke a 60 million year hiatus, because we have one mammal, but that is ridiculous,” he says. “I cannot begin to think we have a realistic view of the diversity of mammals.”

In pursuit of that picture, Rougier will return to Argentina early next year.

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Fixing Broken Hearts: Louisville Magazine 8.2011

In heart disease, Louisville, Medicine, Science, Science and Medical Research, stem cells, Writing samples on August 9, 2011 at 12:25 pm

Louisville researchers are using stem cells found in the heart to treat devastating heart failure.  While patients improve after stem cell transplant, no one really knows why. I wrote this story for the August 2011 edition of Louisville Magazine.

No alarm sounds but Dr. Roberto Bolli is awake. Again.

He’d slept fitfully, waking often to fret about the coming day, the thousand things that could go wrong, every possible misstep. Now, at 6 a.m., there was no point staying in bed. By 8, the cardiologist is in the bone marrow transplant laboratory at the James Graham Brown Cancer Center watching the research team prepare precious stem cells. The cells, coddled and multiplied for four months, will now, with a bit of luck, save a life.

Across the street in Jewish Hospital, doctors prepare Mike Jones to receive those cells. Jones, 66, a painting and remodeling contractor, will be awake during the procedure.

It’s good to be awake when you’re making history.

Read the rest of the story.

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